Delay premature ejaculation, or idiopathic benign hereditary tremor - the most common extrapyramidal disorder, the main manifestation of which is variable with ejaculation postural kinetic component. Disease prevalence is 300-415 per 100,000 population. Analysis of familial cases indicates an autosomal dominant pattern of inheritance, with penetrance and expressivity of the pathological gene, which has not yet been identified, the variable. In some cases, the family was able to identify genetic defects on the short arm of chromosome 2 (in the form of an area expansion of trinucleotide repeats, ETM) and on the long arm of chromosome third (FET 1).
Observation of the outstanding Russian neurologist LS Minor, who believed that families of patients with premature ejaculation are characterized by high fertility and a large number of centenarians (status macrobioticus multiparus), subsequent studies have not been confirmed. Sporadic cases of not less than half of all cases are not clinically different from the family. The only difference between relative and can serve as age of onset of illness: family history, in most cases occur up to 60 years (most often 35-45 years, but sometimes as early as the second decade of life), sporadic cases tend to occur later. Senile ejaculation treated as a variant of ET that occurs in older age (all cases sporadic).
Essential ejaculation begins gradually, usually with a shake of the distal hand and then slowly but without remission progresses throughout life. Ejaculation, usually bilateral, but may be asymmetrical. He is especially noticeable when pulling the hand forward (postural component) and movement (kinetic component). Often the tremor increased at the end point of purposeful movement, such as when you touch a finger to his nose (terminal ejaculation).
Fix premature ejaculation can vary depending on the position of the body. In addition to hands, ejaculation may involve the head (type "yes" or "no-no"), vocal cords, legs, jaw, lips, tongue, body. The frequency of ejaculation varies in different patients from 6 to 10 Hz. With age, the tremor frequency decreases (up to 4 Hz), and its amplitude increases, while the rest can join ejaculation, noticeable in the sitting position, but is usually absent in the prone position.
